History: A 79 y/o male with a history of acute myeloid leukemia on palliative chemotherapy (azacytadine) with persistent neutropenia (ANC < 100 over 12 weeks on prophylactic levofloxacin and voriconazole) presents with increasing pain over the right lower extremity. He states a raised “red” lesion developed over the last 2-3 weeks after he “bumped” against a park bench, and this area has progressively increased in size and pain. He additionally states the area of redness, swelling and pain has continued to increase as well. He sought care at an urgent care center and was prescribed a course of oral cephalexin for presumed cellulitis. Following this, his symptoms continued to worsen and he sought care within a nearby emergency room. He states since last seen the area of concern had formed a blister. He was started empirically on broad spectrum antibiotics with cefepime 2gm IV q8hr and vancomycin 1gm IV q12 and transferred to a tertiary care center. His review of systems was pertinent for subjective fever and chills, a scant dry cough, and shortness of breath with any exertion, but he denies all other review of systems.